Reply to Letter to the Editor Letter to the Editor Reply to

نویسندگان

  • Xujun Chen
  • Xin Chen
چکیده

We appreciate Dr Lentini and co-workers [1] for their comments on our report [2]. Infective endocarditis (IE) involved aortic valve nowadays remains to be associated with high morbidity and mortality [3]. Eradication of infection and correction of the associated haemodynamic abnormality are fundamental to patients indicated for surgical treatment. Valve replacement is the preferred choice of most surgeons for its easy manipulation, but it carries the risk of prosthesisrelated complication. We successfully performed vegetectomy for a patient with IE involving the aortic valve [2]. The patient had no IE recurrence and had a normal-functioning aortic valve at 19 months follow-up. The main advantages of vegetectomy can include preservation of the normal, native valve; preservation of normal haemodynamic function; and abolition of the risks of anticoagulative medication. This procedure is indicated in the aortic valve when IE is in the early stage without an evidence of annular abscess, perforation of valve leaflet or destruction of subvalvular apparatus. The case in our report is not a common phenomenon in the clinic. In our patient, although all vegetations were completely excised with low-strength electrocautery and repeatedly scrubbed with iodophor, normal blood sedimentation rate and repeated negative blood culture could be obtained until antibiotic therapy was continued for 12 weeks [2]. In our view, an in-depth eradication of the infected area by vegetectomy in the three leaflets could be incomplete during surgery. A larger-impact blood flow to the aortic valve than to the other valves can also contribute to recurring infection. Therefore, we agree that vegetectomy may carry the risk of recurrent infection, and, in a selected patient, vegetectomy with valve sparing may be a viable option in early-stage IE involving the aortic valve. We fully agree that vegetectomy can also be used for patients with IE involving the mitral valve. A larger excision of the infected area should be performed during surgery, and therefore a combined surgery such as mitral valve repair is also necessary, as previous reported by Lukács et al. [4]. The authors described that a valve repair was completed by reinforcement and reduction of the posterior ring, and by commissuroplasty. No prosthetic ring, or any other prosthetic material, or polyfilament sutures were used. We appreciate these finer technical aspects. However, duration of 12 months follow-up is inadequate for this patient. According to our experience, the patient would benefit better from implantation of prosthetic ring in mitral valve repair in the long term. References

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تاریخ انتشار 2009